Angiotensin receptor blockers or Angiotensin receptor antagonists are also known as ‘ARBs’, ‘AT1 receptor blockers’ or ‘sartans’. ARBs have similar hypotensive effects that of ACE inhibitors. These drugs mainly use in patient with hypertension or following myocardial infarction. It case vasorelaxation. ARBs are preferred than other antihypertensive agents in diabetic patient because these drugs reduce … Read more
CAPTOPRIL GENERIC NAME: Captopril BRAND NAME: Capoten, Acepril, Capozide GENERAL DESCRIPTION Captopril is the first and potent ACE inhibitors. It is also called vasoactive peptide. It is the only ACE inhibitor that has the capability to enter the central nervous system by crossing the blood brain barrier. Captopril is used as the first line treatment … Read more
ACE Inhibitors or Angiotensin converting enzymes inhibitors are also called vasoactive peptides because of their direct effect on blood vessels. ACE inhibitors are widely used medicine and first line of treatment in hypertension and congestive heart failure. ACE inhibitors decrease systemic vascular resistance without increasing heart rate and also promotes natriuresis. List of Common ACE … Read more
Potassium sparing diuretics Nursing Implications and Drug Study POTASSIUM SPARING DIURETICS GENERAL DESCRIPTION Potassium sparing diuretics caused diuresis without loss of potassium unlike other diuretics. They are less potent diuretic agents therefore potassium sparing diuretics may combine with other diuretics to prevent the loss of potassium and further increase in diuretic effects. EXAMPLE: Potassium sparing … Read more
Thiazide Diuretics Nursing Implications & Drug Study THIAZIDE DIURETICS GENERAL DESCRIPTION Thiazide diuretics appeared as a result to synthesize more potent carbonic anhydrase inhibitors. Like CAI and some loop diuretics, thiazide diuretics also has unsubstituted sulphonamide group which is the main functional group for its diuretic activity. Thiazide diuretics are more effective in patients with … Read more
CARBONIC ANHYDRASE INHIBITORS (CAI) Carbonic Anhydrase Inhibitors Nursing Considerations, Implications & Drug Study GENERAL DESCRIPTION Carbonic anhydrase inhibitors are prototype of modern diuretics and discovered when fond bacteriostatic sulphonamide cause an alkaline diuresis.The prototypical carbonic anhydrase is Acetazolamide. CAI are rarely used diuretics now a days but they still have several other specific applications. It inhibits … Read more
Loop diuretics Nursing Considerations, Implications & Drug Study LOOP DIURETICS GENERAL DESCRIPTION Loop diuretics are the most efficacious diuretics agents available because diuretic effects of loop diuretics are not affected with the development of acidosis in the body like other diuretic agents. Furosemide and ethacrynic acid are the prototypes of loop diuretics. Loop diuretics usually … Read more
Osmotic diuretics: Nursing Care & Drug Study OSMOTIC DIURETICS General Description: Osmotic diuretics are the type of diuretics that induce osmotic diuresis in the kidney and thus decrease the plasma volume and controls blood pressure. Osmotic diuretic contains such type of drugs that are highly permeable and secrets into the lumen and increase solute concentration thus … Read more
Diuretics Nursing Care and Drug Study Diuretics Diuretic is an agent that increases urine volume, while a ‘natriuretic’ causes increase in renal sodium excretion. It is a golden rule, water leads to follow sodium, where sodium goes water follows it, therefore natriuretic are usually called diuretics. Diuretics decreases blood pressure broadly by two actions : by … Read more