PHENYLALKYLAMINE: VERAPAMIL GENERAL DESCRIPTION Verapamil is the first clinically available Calcium channel blocker. It is it is an alkaloid vasodilator. Verapamil is less potent calcium channel blocker than amlodipine but more potent than diltiazem. GENERIC NAME: Verapamil BRAND NAME Calan, Isoptin, Verelan MECHANISM OF ACTION Cardiovascular response of verapamil is shown in following steps Firstly, … Read more
BENZOTHIAZEPINE: DILTIAZEM GENERAL DESCRIPTION Diltiazem is less potent calcium channel blockers than verapamil and dihydrpyridines. It belongs to the benzothiazepine group of calcium channel blockers. Diltiazem is extensively used as antianginal and antiarrhythmic drug. To control tachycardia, diltiazem is also given after antithyroid therapy in such patient where beta blockers are contraindicated. GENERIC NAME: Diltiazem … Read more
Dihyropyridine: Amlodipine GENERAL DESCRIPTION Amlodipine is a good choice of drug for elderly patients. Amlodipine has no effects on heart rate like other calcium channel blockers. Amlodipine is more potent than verapamil and diltiazem. GENERIC NAME: Amlodipine BRAND NAME: Norvasc, Acord, Amlibon MECHANISM OF ACTION Amlodipine produce both peripheral arterial vasodilation and coronary dilation. Cardiovascular … Read more
GENERAL DESCRIPTION Calcium Channel Blockers are used to block voltage-dependent Ca2+ channel are called Calcium channel blockers. The main action of this drug is vasodilation. These drugs are used to treat many cardio vascular disease including hypertension, arrhythmia and angina pectoris. Dihyropyridines are more potent vasodilators than Verapamil, which is more potent than diltiazem. TYPES … Read more