SPIRONOLACTONE GENERIC NAME: Spironolactone BRAND NAME: Aldactone GENERAL DESCRIPTION Spironolactone is a synthetic steroid that act as a competitive antagonist to aldosterone. It is also called potassium sparing diuretics because it prevents the loss of potassium from the body. Prolong use of spironolactone can cause in heart failure and its use is limited when there … Read more
Potassium sparing diuretics Nursing Implications and Drug Study POTASSIUM SPARING DIURETICS GENERAL DESCRIPTION Potassium sparing diuretics caused diuresis without loss of potassium unlike other diuretics. They are less potent diuretic agents therefore potassium sparing diuretics may combine with other diuretics to prevent the loss of potassium and further increase in diuretic effects. EXAMPLE: Potassium sparing … Read more
Thiazide Diuretics Nursing Implications & Drug Study THIAZIDE DIURETICS GENERAL DESCRIPTION Thiazide diuretics appeared as a result to synthesize more potent carbonic anhydrase inhibitors. Like CAI and some loop diuretics, thiazide diuretics also has unsubstituted sulphonamide group which is the main functional group for its diuretic activity. Thiazide diuretics are more effective in patients with … Read more
CARBONIC ANHYDRASE INHIBITORS (CAI) Carbonic Anhydrase Inhibitors Nursing Considerations, Implications & Drug Study GENERAL DESCRIPTION Carbonic anhydrase inhibitors are prototype of modern diuretics and discovered when fond bacteriostatic sulphonamide cause an alkaline diuresis.The prototypical carbonic anhydrase is Acetazolamide. CAI are rarely used diuretics now a days but they still have several other specific applications. It inhibits … Read more
Loop diuretics Nursing Considerations, Implications & Drug Study LOOP DIURETICS GENERAL DESCRIPTION Loop diuretics are the most efficacious diuretics agents available because diuretic effects of loop diuretics are not affected with the development of acidosis in the body like other diuretic agents. Furosemide and ethacrynic acid are the prototypes of loop diuretics. Loop diuretics usually … Read more
Osmotic diuretics: Nursing Care & Drug Study OSMOTIC DIURETICS General Description: Osmotic diuretics are the type of diuretics that induce osmotic diuresis in the kidney and thus decrease the plasma volume and controls blood pressure. Osmotic diuretic contains such type of drugs that are highly permeable and secrets into the lumen and increase solute concentration thus … Read more
Diuretics Nursing Care and Drug Study Diuretics Diuretic is an agent that increases urine volume, while a ‘natriuretic’ causes increase in renal sodium excretion. It is a golden rule, water leads to follow sodium, where sodium goes water follows it, therefore natriuretic are usually called diuretics. Diuretics decreases blood pressure broadly by two actions : by … Read more